Hemorrhage associated with "bone crisis" in Gaucher's disease identified by magnetic resonance imaging

Gadi Horev*, Leora Kornreich, Herzeliah Hadar, Kalman Katz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Children suffering from Gaucher's disease were examined by magnetic resonance imaging (MRI) during a characteristic episode of "bone crisis". An unexpectedly high intramedullary as well as subperiosteal signal was observed on both the T1 and T2-weighted sequences in 5 patients, suggesting a subacute hemorrhage or hematoma. It is conceivable that such a painful hemorrhage is an important component of the "bone crisis" phenomenon. Furthermore, in these cases this is a specific sign which may enable differentiation of bone crises from other types of bone pain associated with Gaucher's disease.

Original languageEnglish
Pages (from-to)479-482
Number of pages4
JournalSkeletal Radiology
Volume20
Issue number7
DOIs
StatePublished - Oct 1991
Externally publishedYes

Keywords

  • Bone hemorrhage
  • Gaucher's disease
  • Magnetic resonance imaging

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