TY - JOUR
T1 - Hemodynamic characteristics in women undergoing in vitro fertilization cycles a prospective study
AU - Baruch, Yoav
AU - Ashwal, Eran
AU - Hasson, Joseph
AU - Avraham, Sarit
AU - Amikam, Uri
AU - Blecher, Yair
AU - Avnon, Tomer
AU - Dviri, Michal
AU - Many, Ariel
AU - Azem, Foad
N1 - Publisher Copyright:
© Journal of Reproductive Medicine®, Inc.
PY - 2021/8
Y1 - 2021/8
N2 - OBJECTIVE: To analyze the hemodynamic characteristics in women undergoing in vitro fertilization (IVF) cycles. STUDY DESIGN: A prospective study conducted at a university affiliated ter-tiary hospital. Eighty-one women underwent a total of 106 cycles of controlled ovarian hyperstimulation, and 27 women underwent frozen-thawed embryo transfer (FET) cycles. A nonin-vasive cardiac system device (NICaS) was used to assess hemodynamic characteristics at baseline before stimula-tion (Time 0), at ovum pick-up (OPU) day (Time 1), and at embryo transfer (ET) day (Time 2). For FET cycles, measurements were recorded at recruitment (Time A) and just before ET (Time B). RESULTS: In fresh cycles, no significant differences in all parameters were noted between Times 0 and 1. A significant increase in cardiac index was, however, noted at Time 2 (14.7%) as compared to Times 1 and 0 (11.5%) (p=0.029). Heart rate was higher at Time 2 as compared to Times 0 and 1 (by 10.9% and 9.7%, respec- tively; p<0.001). In FET cycles, no differences were noted in all parameters between Time A and Time B. CONCLUSION: Significant hemodynamic differences were recorded only at the ET stage of fresh cycles, con-trasted to no change at OPU or along FET cycles. These changes plausibly reflect the influence of vasoactive sub-stances secreted from aspi-rated follicles. (J Reprod Med 2021;66:176–182).
AB - OBJECTIVE: To analyze the hemodynamic characteristics in women undergoing in vitro fertilization (IVF) cycles. STUDY DESIGN: A prospective study conducted at a university affiliated ter-tiary hospital. Eighty-one women underwent a total of 106 cycles of controlled ovarian hyperstimulation, and 27 women underwent frozen-thawed embryo transfer (FET) cycles. A nonin-vasive cardiac system device (NICaS) was used to assess hemodynamic characteristics at baseline before stimula-tion (Time 0), at ovum pick-up (OPU) day (Time 1), and at embryo transfer (ET) day (Time 2). For FET cycles, measurements were recorded at recruitment (Time A) and just before ET (Time B). RESULTS: In fresh cycles, no significant differences in all parameters were noted between Times 0 and 1. A significant increase in cardiac index was, however, noted at Time 2 (14.7%) as compared to Times 1 and 0 (11.5%) (p=0.029). Heart rate was higher at Time 2 as compared to Times 0 and 1 (by 10.9% and 9.7%, respec- tively; p<0.001). In FET cycles, no differences were noted in all parameters between Time A and Time B. CONCLUSION: Significant hemodynamic differences were recorded only at the ET stage of fresh cycles, con-trasted to no change at OPU or along FET cycles. These changes plausibly reflect the influence of vasoactive sub-stances secreted from aspi-rated follicles. (J Reprod Med 2021;66:176–182).
KW - Assisted reproductive technology
KW - Cardiac output
KW - Controlled ovarian hyperstimulation
KW - Echocardiography, Dop-pler
KW - Hemodynamics
KW - IVF
KW - Im-pedance
KW - In vitro fertilization
KW - Monitoring, instrumentation
KW - Ovarian hyperstimulation syn-drome
UR - http://www.scopus.com/inward/record.url?scp=85119595025&partnerID=8YFLogxK
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AN - SCOPUS:85119595025
SN - 0024-7758
VL - 66
SP - 176
EP - 182
JO - The Journal of reproductive medicine
JF - The Journal of reproductive medicine
IS - 7-8
ER -
