Hematological Manifestations among Patients with Rheumatic Diseases

Alina Klein*, Yair Molad

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Background: Rheumatic diseases have many hematological manifestations. Blood dyscrasias and other hematological abnormalities are sometimes the first sign of rheumatic disease. In addition, novel antirheumatic biological agents may cause cytopenias. Summary: The aim of this review was to discuss cytopenias caused by systemic lupus erythematosus and antirheumatic drugs, Felty's syndrome in rheumatoid arthritis, and autoimmune hemolytic anemia, thrombosis, and thrombotic microangiopathies related to rheumatological conditions such as catastrophic antiphospholipid syndrome and scleroderma renal crisis. Key Message: The differential diagnosis of various hematological disorders should include rheumatic autoimmune diseases among other causes of blood cell and hemostasis abnormalities. It is crucial that hematologists be aware of these presentations so that they are diagnosed and treated in a timely manner.

Original languageEnglish
Pages (from-to)403-412
Number of pages10
JournalActa Haematologica
Volume144
Issue number4
DOIs
StatePublished - 1 Jul 2021

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