The hygiene theory represents environmental aspects that modulate the risk for developing autoimmune diseases. There is a reverse correlation between the presence of helminthes and the flare of autoimmune diseases, explaining the rise in the incidence of certain autoimmune diseases in developed countries. The protective properties of certain helminths is attributed to their secretory compounds that immunomodulate the host immune system to survive. The chapter provides a glimpse on several helminth-secrteted products that has a role in the immunomodulation of the host immune network.
|Title of host publication||Mosaic of Autoimmunity|
|Subtitle of host publication||The Novel Factors of Autoimmune Diseases|
|Number of pages||4|
|State||Published - 13 Feb 2019|
- Murine models
- Secretory molecules