Helicobacter pylori infection is associated with low serum ferritin levels in Israeli Arab children-A seroepidemiologic study

Khitam Muhsen, Mira Barak, Luba Shifnaidel, Avishag Nir, Ravit Bassal, Dani Cohen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We examined the association between Helicobacter pylori seropositivity and low ferritin levels in sera of 509 Israeli Arab children aged 1 to 19 years. Serum ferritin levels were measured using the immunoturbidity assay. ELISA was used to detect serum IgG antibodies to H pylori and IgG antibodies to H pylori CagA strains. Low ferritin level was found between 14.5% and 8.6% of the H pylori seropositive and seronegative participants, respectively (P = 0.035). A trend for a higher frequency of low ferritin was detected among H pylori-CagA seropositive children. Multivariate analysis showed an increased frequency of low ferritin only among children younger than or equal to 5 years: adjusted OR 4.62 (95% CI 1.53-13.99) P = 0.007.

Original languageEnglish
Pages (from-to)262-264
Number of pages3
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume49
Issue number2
DOIs
StatePublished - Aug 2009

Keywords

  • Children
  • H pylori
  • Seroepidemiology
  • Serum ferritin

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