TY - JOUR
T1 - Heat-induced changes in the rat parotid gland
AU - Horowitz, Michal
AU - Mittelman, G.
AU - Oron, Y.
N1 - Funding Information:
Acknowledgements-This investigationw as supportedb y the Joint Research Fund of the Hebrew University HadassahS choolo f DentalM edicinef oundedb y theA lpha OmegaF raternitya nd the HadassahM edical Organization and by a grant from the SchreiberF oundation(Tel-Aviv University)P. art of this work wasd onea s a requiremenfto r the award of the D.Md. degreet o G.M.
PY - 1983
Y1 - 1983
N2 - Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.
AB - Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.
UR - http://www.scopus.com/inward/record.url?scp=0020982673&partnerID=8YFLogxK
U2 - 10.1016/0003-9969(83)90059-6
DO - 10.1016/0003-9969(83)90059-6
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AN - SCOPUS:0020982673
SN - 0003-9969
VL - 28
SP - 1037
EP - 1041
JO - Archives of Oral Biology
JF - Archives of Oral Biology
IS - 11
ER -