Heat-induced changes in the rat parotid gland

Michal Horowitz*, G. Mittelman, Y. Oron

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 °C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.

Original languageEnglish
Pages (from-to)1037-1041
Number of pages5
JournalArchives of Oral Biology
Volume28
Issue number11
DOIs
StatePublished - 1983

Funding

FundersFunder number
HadassahM edical Organization
Joint Research Fund of the Hebrew University
SchreiberF oundation
Tel Aviv University

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