Hearing loss as the presenting feature of systemic vasculitis

Merav Lidar, Eldar Carmel, Yona Kronenberg, Pnina Langevitz*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Hearing loss, both sensorineural and conductive, is a well-recognized manifestation of systemic vasculitis, yet has only infrequently been described as its initial presentation. We describe three cases in which hearing loss preceded the diagnosis of systemic vasculitis by a period of a few weeks to more than 6 months. While steroid therapy was initiated immediately in one of the cases, comprehensive immunosuppressive therapy was given only after additional manifestations compatible with vasculitis appeared, allowing for a diagnosis of Wegener's granulomatosis in two of the cases and undifferentiated vasculitis, in the third. Hearing improved in all patients, albeit, residual dysfunction remained. Prompt referral for a complete rheumatologic workup in cases of unexplained hearing loss would allow for a timely diagnosis of a collagen vascular disease and facilitate early initiation of systemic therapy, possibly yielding better audiological results.

Original languageEnglish
Title of host publicationAutoimmunity, Part C The Mosaic of Autoimmunity
PublisherBlackwell Publishing Inc.
Number of pages6
ISBN (Print)1573316628, 9781573316620
StatePublished - Jun 2007
Externally publishedYes

Publication series

NameAnnals of the New York Academy of Sciences
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632


  • Conductive
  • Hearing loss
  • Sensorineural
  • Systemic vasculitis


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