TY - JOUR
T1 - HBV vaccine and dermatomyositis
T2 - Is there an association?
AU - Altman, Arie
AU - Szyper-Kravitz, Martine
AU - Shoenfeld, Yehuda
PY - 2008/4
Y1 - 2008/4
N2 - The etiology of dermatomyositis is unknown, but immune mechanisms play an important role. Several dermatological manifestations have been reported among carriers of hepatitis B surface antigen, and after vaccination with the HBV vaccine. Almost all the skin reactions described were peculiar skin eruptions suggestive of an immune complex reaction. Some authors described the occurrence of dermatomyositis after BCG and influenza vaccination. We report a case of a 6-year-old child, who was vaccinated for hepatitis B virus and developed a flu-like disease accompanied by a skin rash, which had the typical features of dermatomyositis. The association of vaccination with autoimmunity is discussed.
AB - The etiology of dermatomyositis is unknown, but immune mechanisms play an important role. Several dermatological manifestations have been reported among carriers of hepatitis B surface antigen, and after vaccination with the HBV vaccine. Almost all the skin reactions described were peculiar skin eruptions suggestive of an immune complex reaction. Some authors described the occurrence of dermatomyositis after BCG and influenza vaccination. We report a case of a 6-year-old child, who was vaccinated for hepatitis B virus and developed a flu-like disease accompanied by a skin rash, which had the typical features of dermatomyositis. The association of vaccination with autoimmunity is discussed.
KW - Autoimmunity
KW - Dermatomyositis
KW - HBV vaccine
KW - Hepatitis virus
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=41049114580&partnerID=8YFLogxK
U2 - 10.1007/s00296-007-0485-4
DO - 10.1007/s00296-007-0485-4
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AN - SCOPUS:41049114580
SN - 0172-8172
VL - 28
SP - 609
EP - 612
JO - Rheumatology International
JF - Rheumatology International
IS - 6
ER -
