HBV vaccine and dermatomyositis: Is there an association?

Arie Altman, Martine Szyper-Kravitz, Yehuda Shoenfeld*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The etiology of dermatomyositis is unknown, but immune mechanisms play an important role. Several dermatological manifestations have been reported among carriers of hepatitis B surface antigen, and after vaccination with the HBV vaccine. Almost all the skin reactions described were peculiar skin eruptions suggestive of an immune complex reaction. Some authors described the occurrence of dermatomyositis after BCG and influenza vaccination. We report a case of a 6-year-old child, who was vaccinated for hepatitis B virus and developed a flu-like disease accompanied by a skin rash, which had the typical features of dermatomyositis. The association of vaccination with autoimmunity is discussed.

Original languageEnglish
Pages (from-to)609-612
Number of pages4
JournalRheumatology International
Volume28
Issue number6
DOIs
StatePublished - Apr 2008

Keywords

  • Autoimmunity
  • Dermatomyositis
  • HBV vaccine
  • Hepatitis virus
  • Vaccine

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