Hamster endogenous retrovirus (HaER) isolated from SV-40 induced tumor cells

Anna Goldschmied-Reouven*, A. Yaniv, K. Perk

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A hamster cell line obtained from a secondary transplanted SV-40-induced tumor was found to spontaneously release type C virus particles. The particles possessed all biochemical features characteristic of retroviruses and induced syncytium formation in XC cells but were not oncogenic for hamsters. Nucleic acid hybridization assays demonstrated that the isolated virus was an endogenous retrovirus of hamster, lacking sequence homology with mouse and other animal species.

Original languageEnglish
Pages (from-to)233-244
Number of pages12
JournalArchives of Virology
Volume78
Issue number3-4
DOIs
StatePublished - Sep 1983

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