TY - JOUR
T1 - Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis
AU - Kashman, Yoel
AU - Koren-Goldshlager, Ganit
AU - Gravalos, M. D.Garcia
AU - Schleyer, Michael
PY - 1999/1/29
Y1 - 1999/1/29
N2 - Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-28 in concentrations of 12-25 ng/ml.
AB - Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-28 in concentrations of 12-25 ng/ml.
UR - http://www.scopus.com/inward/record.url?scp=0033613698&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(98)02467-8
DO - 10.1016/S0040-4039(98)02467-8
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AN - SCOPUS:0033613698
SN - 0040-4039
VL - 40
SP - 997
EP - 1000
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 5
ER -