TY - JOUR
T1 - Guanosine 3',5'-bispyrophosphate (ppGpp) synthesis in cells of Escherichia coli starved for P(i)
AU - Spira, B.
AU - Silberstein, N.
AU - Yagil, E.
PY - 1995
Y1 - 1995
N2 - Cells of Escherichia coli which enter a phase of starvation for P(i) induce the synthesis of the nucleotide guanosine 3',5'-bispyrophosphate (ppGpp). This induction is relA independent but depends on the spot gene product. A mutant unable to produce ppGpp is impaired in the expression of two genes which belong to the pho regulon, a defect which is dependent on the product of spoT. We suggest that ppGpp is essential for the proper induction of the genes which belong to the pho regulon.
AB - Cells of Escherichia coli which enter a phase of starvation for P(i) induce the synthesis of the nucleotide guanosine 3',5'-bispyrophosphate (ppGpp). This induction is relA independent but depends on the spot gene product. A mutant unable to produce ppGpp is impaired in the expression of two genes which belong to the pho regulon, a defect which is dependent on the product of spoT. We suggest that ppGpp is essential for the proper induction of the genes which belong to the pho regulon.
UR - http://www.scopus.com/inward/record.url?scp=0029079412&partnerID=8YFLogxK
U2 - 10.1128/jb.177.14.4053-4058.1995
DO - 10.1128/jb.177.14.4053-4058.1995
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AN - SCOPUS:0029079412
SN - 0021-9193
VL - 177
SP - 4053
EP - 4058
JO - Journal of Bacteriology
JF - Journal of Bacteriology
IS - 14
ER -