Grafts of HTR Polymer Versus Kiel Bone in Experimental Long Bone Defects in Rats

Itzhak Binderman, M. Goldstein, I. Horowitz, N. Fine, S. Taicher, Arthur Ashman, A. Shteyer

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Gaps were prepared surgically in femora of 42 albino rats, and were kept apart by a looped wire. Grafts of Kiel bone (KB) and HTR™ polymer in different environments were implanted into those gaps. The control groups showed a nonbony healing 36 days after the osteotomy. KB or HTR polymer alone failed to induce bone bridging, while KB with autologous bone marrow induced bone bridging in the gaps. The most significant finding in this study was the ability of calcium hydroxide [Ca(OH)2] grafted with either KB or HTR polymer to cause differentiation of bone matrix in the surgical gaps. The combination of HTR polymer and Ca(OH)2induced formation of trabecular bone bridging to a greater extent than all the other material combinations.

Original languageEnglish
Title of host publicationQuantitative Characterization and Performance of Porous Implants for Hard Tissue Applications
EditorsJack E. Lemons
PublisherASTM International
Pages370-376
Number of pages7
ISBN (Electronic)9780803109650
DOIs
StatePublished - 1987
Externally publishedYes
Event1985 Symposium on Quantitative Characterization and Performance of Porous Implants for Hard Tissue Applications - Nashville, United States
Duration: 18 Nov 198519 Nov 1985

Publication series

NameASTM Special Technical Publication
VolumeSTP 953
ISSN (Print)0066-0558

Conference

Conference1985 Symposium on Quantitative Characterization and Performance of Porous Implants for Hard Tissue Applications
Country/TerritoryUnited States
CityNashville
Period18/11/8519/11/85

Keywords

  • HTR polymer
  • Kiel bone
  • calcium hydroxide effect on grafts
  • experimental bone gap healing
  • porous implants

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