Gradenigo's syndrome: Is fusobacterium different? Two cases and review of the literature

Merav Heshin-Bekenstein*, Orli Megged, Uri Peleg, Sarit Shahroor-Karni, Roman Bass, Moni Benifla, Maskit Bar-Meir

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Gradenigo's syndrome is a rare but life threatening complication of acute otitis media (AOM), which ncludes a classic triad of otitis media, deep facial pain and ipsilateral abducens nerve paralysis. The ncidence of Fusobacterium necrophorum infections has increased in recent years. We describe two cases f Gradenigo's syndrome caused by F. necrophorum. Additional four cases were identified in a review of he literature. Gradenigo's syndrome as well as other neurologic complications should be considered in ases of complicated acute otitis media. F. necrophorum should be empirically treated while awaiting culture results.

Original languageEnglish
Pages (from-to)166-169
Number of pages4
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number1
StatePublished - Jan 2014
Externally publishedYes


  • Acute otitis media
  • Fusobacterium necrophorum
  • Gradenigo's syndrome
  • Petrous apecitis


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