Good results of circumferential spine fusion in smokers, using autograft and allograft

Y. Mirovsky*, N. Halperin, Y. Anekstein, M. G. Neuwirth

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We have examined the rates of anterior interbody fusion of lumbar spine segments following fusion with a fresh frozen, femoral head allograft in 25 heavy smoking patients. They were all stabilized both anteriorly and posteriorly. The indications for surgery were: degenerative disc disease, degenerative spondylolisthesis and nonunion following previous posterolateral fusion of lumbar spine segments. Only patients who had fusion of one or two lumbar segments were included. They all were stabilized posteriorly with pedicle screws and autogenic iliac bone graft. The fusion was assessed at least one year after surgery according to plan X-rays as "Solid", "Questionable" or "Failure". One patient was found at follow up not fused, in another one the fusion was "questionable" and all the other 23 patients had an anterior solid fusion. Clinically, 84% of the patients had the same or improved work status as before surgery and 68% acknowledged that they were satisfied with the surgical results. No major complications were recorded and the average length of hospitalization was 10.3 day.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalCell and Tissue Banking
Issue number3
StatePublished - 2002
Externally publishedYes


  • Cigarette smoking
  • Fresh-frozen graft
  • Lumbar spine
  • Nicotine
  • Nonunion
  • Pseudarthrosis
  • Spine fusion


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