TY - JOUR
T1 - Go-no-go performance in pathological gamblers
AU - Kertzman, Semion
AU - Lowengrub, Katherine
AU - Aizer, Anat
AU - Vainder, Michael
AU - Kotler, Moshe
AU - Dannon, Pinhas N.
PY - 2008/10/30
Y1 - 2008/10/30
N2 - Previous neuropsychological studies demonstrated various deficits of impulse control in pathological gamblers (PGs). However, there are limited data available on response-inhibition impairment among PGs. The present study attempted to assess response inhibition in untreated PGs (N = 83), in comparison with normal subjects (N = 84). Go/no-go and target-detection conditions of a computerized task were used as a measure of response-inhibition ability. A repeated measures analysis of covariance (ANCOVA-RM) was used with response time, variability of response time, and number of false alarms and misses as dependent measures; group (PG and controls) as the between-subjects measure; condition (target detection or go/no-go) and time slice (first and second in each condition) as repeated measures within-subject factors; and educational level as a covariate. Our results showed that PGs were significantly more impaired in both target detection and go/no-go task performance than controls. The PGs had significantly more false alarms and misses than controls, and they were slower and less consistent in their responses.
AB - Previous neuropsychological studies demonstrated various deficits of impulse control in pathological gamblers (PGs). However, there are limited data available on response-inhibition impairment among PGs. The present study attempted to assess response inhibition in untreated PGs (N = 83), in comparison with normal subjects (N = 84). Go/no-go and target-detection conditions of a computerized task were used as a measure of response-inhibition ability. A repeated measures analysis of covariance (ANCOVA-RM) was used with response time, variability of response time, and number of false alarms and misses as dependent measures; group (PG and controls) as the between-subjects measure; condition (target detection or go/no-go) and time slice (first and second in each condition) as repeated measures within-subject factors; and educational level as a covariate. Our results showed that PGs were significantly more impaired in both target detection and go/no-go task performance than controls. The PGs had significantly more false alarms and misses than controls, and they were slower and less consistent in their responses.
KW - Attention
KW - Continuous performance task
KW - Pathological gamblers
KW - Speed-accuracy tradeoff
KW - Target detection
UR - http://www.scopus.com/inward/record.url?scp=52149110319&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2007.06.026
DO - 10.1016/j.psychres.2007.06.026
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AN - SCOPUS:52149110319
SN - 0165-1781
VL - 161
SP - 1
EP - 10
JO - Psychiatry Research
JF - Psychiatry Research
IS - 1
ER -