GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

Dov Feldberg, Gil A. Goldman, Dov Dicker, Jacob Ashkenazi, Michal Shelef, Jack A. Goldman

Research output: Contribution to journalArticlepeer-review

Abstract

Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

Original languageEnglish
Pages (from-to)111-116
Number of pages6
JournalEuropean Journal of Obstetrics, Gynecology and Reproductive Biology
Volume39
Issue number2
DOIs
StatePublished - 16 Apr 1991

Keywords

  • GnRH analogue
  • In vitro fertilization
  • Pregnancy potential

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