GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

Dov Feldberg; Gil A. Goldman; Dov Dicker; Jacob Ashkenazi; Michal Shelef; Jack A. Goldman

doi:10.1016/0028-2243(91)90073-T

GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

Dov Feldberg, Gil A. Goldman, Dov Dicker, Jacob Ashkenazi, Michal Shelef, Jack A. Goldman

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Abstract

Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

Original language	English
Pages (from-to)	111-116
Number of pages	6
Journal	European Journal of Obstetrics, Gynecology and Reproductive Biology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1016/0028-2243(91)90073-T
State	Published - 16 Apr 1991

Keywords

GnRH analogue
In vitro fertilization
Pregnancy potential

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10.1016/0028-2243(91)90073-T

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abstract = "Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.",

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AU - Goldman, Gil A.

AU - Dicker, Dov

AU - Ashkenazi, Jacob

AU - Shelef, Michal

AU - Goldman, Jack A.

PY - 1991/4/16

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AB - Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

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GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

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Keywords

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