GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

Dov Feldberg; Gil A. Goldman; Dov Dicker; Jacob Ashkenazi; Michal Shelef; Jack A. Goldman

doi:10.1016/0028-2243(91)90073-T

GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

Dov Feldberg, Gil A. Goldman, Dov Dicker, Jacob Ashkenazi, Michal Shelef, Jack A. Goldman^*

^*Corresponding author for this work

Clinical Departments

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Abstract

Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

Original language	English
Pages (from-to)	111-116
Number of pages	6
Journal	European Journal of Obstetrics and Gynecology and Reproductive Biology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1016/0028-2243(91)90073-T
State	Published - 16 Apr 1991

Keywords

GnRH analogue
In vitro fertilization
Pregnancy potential

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10.1016/0028-2243(91)90073-T

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title = "GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study",

abstract = "Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.",

keywords = "GnRH analogue, In vitro fertilization, Pregnancy potential",

author = "Dov Feldberg and Goldman, \{Gil A.\} and Dov Dicker and Jacob Ashkenazi and Michal Shelef and Goldman, \{Jack A.\}",

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GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study. / Feldberg, Dov; Goldman, Gil A.; Dicker, Dov et al.
In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 39, No. 2, 16.04.1991, p. 111-116.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination

T2 - a comparative study

AU - Feldberg, Dov

AU - Goldman, Gil A.

AU - Dicker, Dov

AU - Ashkenazi, Jacob

AU - Shelef, Michal

AU - Goldman, Jack A.

PY - 1991/4/16

Y1 - 1991/4/16

N2 - Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

AB - Preincubation of oocytes aspirated from follicles in IVF-ET programs is a controversial approach. While some investigators recommend this technique others doubt its necessity. We have studied the embryo quality in 100 women, undergoing IVF-ET, in whom ovulation was induced by the combination of GnRH agonists (GnRHa) and menotropins and compared to a control group in whom ovulation was induced with menotropins alone. No statistically significant difference was noted with regard to the fertilization and cleavage rates as well as to the preincubation period. Significantly higher pregnancy rates (P < 0.001) were encountered in the first group in comparison with the control group.

KW - GnRH analogue

KW - In vitro fertilization

KW - Pregnancy potential

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GnRH agonist increases pregnancy potential of retrieved oocytes given adequate preincubation before insemination: a comparative study

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Keywords

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