@article{d24e6fab7954459eb22a41cbf1957452,
title = "Glycosaminoglycans in follicular fluid from women undergoing in vitro fertilization and their relationship to cumulus expansion, fertilization, and development",
abstract = "The glycosaminoglycans (GAGs) chondroitin sulfate (CS) and heparan sulfate (HS) were assayed in fluid from 178 individual follicles obtained from women after human menopausal gonadotropin ovulation induction for subsequent in vitro fertilization. CS and HS concentrations ranged from 0 to 3.9 and 0 to 18.6 mg/ml, respectively. The percentage of oocytes fertilized was significantly higher when CS concentrations ranged from 0.3 to 0.8 mg/ml (P < 0.03). As HS levels increased, maturation scores by visual assessment of the egg-corona-cumulus cell complexes increased (P < 0.05), but the percentage of oocytes fertilized was not affected. Cleavage rates of developing embryos were not related to the concentrations of GAGs.",
author = "Bellin, \{M. E.\} and Ax, \{R. L.\} and N. Laufer and Tarlatzis, \{B. C.\} and DeCherney, \{A. H.\} and D. Feldberg and Haseltine, \{F. P.\}",
note = "Funding Information: Received January 21, 1985; revised and accepted October 17,1985. *Supported by the University of Wisconsin College of Agricultural and Life Sciences, Hatch grant 2778, and the Graduate School. tDepartment of Dairy Science, University of Wisconsin. :j:Reprint requests: Mary E. Bellin, B.S., Project Specialist, Department of Dairy Science, University of Wisconsin, 266 Animal Sciences Building, 1675 Observatory Drive, Madison, Wisconsin 53706. §Endocrine and Reproductive Biology Sections, Department of Obstetrics and Gynecology, Yale University School of Medicine.",
year = "1986",
doi = "10.1016/s0015-0282(16)49162-4",
language = "אנגלית",
volume = "45",
pages = "244--248",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "2",
}