Glycogen and enzymes of glycogen metabolism in rat embryos and fetal organs

Jose Gutierrez-Correa, Moshe Hod, Janet V. Passoneau*, Norbert Freinkel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Glycogen content and the enzymes of glycogen metabolism have been measured in the post implantation rat embryo over a period ranging from 9.5 to 18.5 days of gestation. The earliest periods studied were at days 9.5 and 10.5 of gestation, when the yolk sac becomes vascularized and heart beat is first established. The next intervals were at days 11.5 when vascular connections via the allantoic placenta are formed. At 14.5 and 18.5 days of development, 4 entire organs were analyzed: heart, liver, kidney and brain. The metabolic apparatus of glycogen metabolism was concentrated in the embryo at 10.5 days, then the heart region, and in the heart itself at later stages.

Original languageEnglish
Pages (from-to)294-302
Number of pages9
Issue number5
StatePublished - 1991


FundersFunder number
National Institute of Diabetes and Digestive and Kidney DiseasesR01DK010699


    • Glycogen
    • Rat embryo
    • Rat fetus


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