@article{bc1265950f7442588869ea6af2c08d18,
title = "Glycans to improve efficacy and solubility of protein aggregation inhibitors",
author = "Ashim Paul and Daniel Segal and Elsa Zacco",
note = "Funding Information: glycan hybrid molecules mitigated Alliance Family Trust 縁?o DS 缃堀 AP is recipient O 爀GalNAc glycosylation 堀 Carbohydr Res P ? aggregationof the targetamyloids?leadingto of a fellowship from the Aufzien Family Losev Y, Paul A, Frenkel-Pinter M, Abu-Hussein M, 53. and non ?toxicoligomers 堀 Themost effectivthe formationoffewer?smaller?amorphouCenes ter for the Prevention and Treatment of Khalaila I, Gazit E, Segal D (2019) Novel model hybrid molecule contained tryptophan Parkinson ? s Disease 縀APPD 缃堀 E? has received of secreted human tau protein reveals the Funding Information: modifications, we explored the conjugation brain-barrier penetration and metabolic targetthe aggregationofintrinsicallydisordered of three galactosylamine variants to Lin C, Chen EHL, Lee LYL, Hsu RL, Luh FY, Yang LL, stability, compared tocurrently-used smallproteins. ACS Comb Sci 18:144-153. tryptophan as novel hybrid agents to target Chou CF, Huang LDe, Lin CC, Chen RPY (2014) molecule inhibitors of protein aggregation ? Aβ and islet amyloid polypeptide aggregation Comparison of the anti 爁ȁ?yloidogenic effect (Paul et al., 2020a). All tested tryptophan-by the Israel Ministry of Science and the of O 爁甁ȁ瘁瘁紁?ylation 唀 O 爁?alactosylation 唀 and The present work was partially supported",
year = "2021",
month = nov,
doi = "10.4103/1673-5374.310688",
language = "אנגלית",
volume = "16",
pages = "2215--2216",
journal = "Neural Regeneration Research",
issn = "1673-5374",
publisher = "Wolters Kluwer Medknow Publications",
number = "11",
}