TY - JOUR
T1 - Glycan Microarray Reveal the Sweet Side of Cancer Vaccines
AU - Padler-Karavani, Vered
N1 - Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/12/22
Y1 - 2016/12/22
N2 - Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.
AB - Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.
UR - http://www.scopus.com/inward/record.url?scp=85006860809&partnerID=8YFLogxK
U2 - 10.1016/j.chembiol.2016.12.002
DO - 10.1016/j.chembiol.2016.12.002
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AN - SCOPUS:85006860809
SN - 2451-9456
VL - 23
SP - 1446
EP - 1447
JO - Cell Chemical Biology
JF - Cell Chemical Biology
IS - 12
ER -
