TY - JOUR
T1 - Glutathione XI. Species variation of membrane diffusion coefficients derived from intracellular thiol oxidation with DIP homologs
AU - Kosower, Nechama S.
AU - Kosower, Edward M.
AU - Levi, Lilly
PY - 1975/8/4
Y1 - 1975/8/4
N2 - The membrane diffusion coefficients of DIP homologs (diazenedicarboxylic acid bis (N′-alkylpiperazides, e.g., N′-alkyl = ethyl) (I) vary substantially in red cells of different species. The coefficients range from 2.0 to 23.0 cm2/sec × 109 at 1°C (sheep r.b.c., chimpanzee r.b.c.) and the increase is correlated with increasing fluidity of the membrane, as indicated by a "fluidity factor" based on the double bond content of the fatty acids of the membrane. High variability of the coefficient in rabbits might be related to cholesterol content.
AB - The membrane diffusion coefficients of DIP homologs (diazenedicarboxylic acid bis (N′-alkylpiperazides, e.g., N′-alkyl = ethyl) (I) vary substantially in red cells of different species. The coefficients range from 2.0 to 23.0 cm2/sec × 109 at 1°C (sheep r.b.c., chimpanzee r.b.c.) and the increase is correlated with increasing fluidity of the membrane, as indicated by a "fluidity factor" based on the double bond content of the fatty acids of the membrane. High variability of the coefficient in rabbits might be related to cholesterol content.
UR - http://www.scopus.com/inward/record.url?scp=0016700177&partnerID=8YFLogxK
U2 - 10.1016/S0006-291X(75)80470-0
DO - 10.1016/S0006-291X(75)80470-0
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AN - SCOPUS:0016700177
SN - 0006-291X
VL - 65
SP - 901
EP - 906
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -