Glucose measurements in solutions using fiberoptic evanescent wave spectroscopy and tunable CO2 laser

Yaron Gotshal*, Ido Adam, Abraham Katzir

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

There is an interest in using infrared spectroscopy techniques for blood analysis, and in particular for glucose measurements. Glucose concentration in aqueous solutions were measured using fiberoptic evanescent wave spectroscopy. A new spectrometer consisting of tunable CO2 laser as the radiation source, and a silver halide fiber was built. Several solutions were measured for calibration with concentrations in the range of 70-2000 mg/dl. After the calibration, solution were measured and predicted according to the calibration parameters. The predicted concentrations were in agreement with the reference ones. The predicted errors for concentrations range up to 200 mg/dl, which is the clinical range, was less then 18 mg/dl (a relative error of about 12%). The AgClBr fibers are non-toxic and therefore This measurement can be carried out in real-time, for in-situ measurements of glucose in blood.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3262
DOIs
StatePublished - 1998
EventProceedings of Surgical-Assist Systems - San Jose, CA, United States
Duration: 25 Jan 199828 Jan 1998

Keywords

  • Glucose
  • IR spectroscopy
  • Optical fibers
  • Silver halide
  • Tunable CO laser

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