Global quantification exposes abundant low-level off-target activity by base editors

Keyphrases

• Off-target Effects 100%
• Base Editor 100%
• Transcriptome 50%
• Target RNA 33%
• Off-target Events 33%
• Number of Sites 16%
• Invisible 16%
• Single-base Resolution 16%
• Methods for Detection 16%
• Pathogenic mutations 16%
• Complementary Approach 16%
• Computational Tools 16%
• Site-directed mutation 16%
• Computational Approach 16%
• Genomic Variation 16%
• RNA mutation 16%
• Guide RNA (gRNA) 16%
• Futures Basis 16%

Biochemistry, Genetics and Molecular Biology

• Transcriptome 100%
• RNA 33%
• Guide RNA 33%
• RNA Mutation 33%
• Genomics 33%