Giant lysosome like structures in promyelocytic leukemia. Ultrastructural and cytochemical observations

U. Mintz, M. Djaldetti, L. Rozenszajn, J. Pinkhas, A. de Vries

Research output: Contribution to journalArticlepeer-review

Abstract

Electron microscopic and cytochemical studies were performed on the promyelocytes of a patient with acute promyelocytic leukemia and disseminated intravascular coagulation. Light and electron microscopic examination of the promyelocytes revealed the presence of both giant granules and Auer bodies. The promyelocytic giant granules and the Auer bodies exhibited cytochemical reactions, indicating the lysosomal nature of both. A common origin of these abnormal lysosomal structures and their possible relation to the coagulation disturbance is considered.

Original languageEnglish
Pages (from-to)426-430
Number of pages5
JournalBiomedicine Express
Volume19
Issue number10
StatePublished - 1973
Externally publishedYes

Fingerprint

Dive into the research topics of 'Giant lysosome like structures in promyelocytic leukemia. Ultrastructural and cytochemical observations'. Together they form a unique fingerprint.

Cite this