TY - JOUR
T1 - Giant cranial and cerebellar hemangioma treated with propranolol
AU - Benvenisti, Haggai
AU - Ben-Sira, Liat
AU - Constantini, Shlomi
AU - Roth, Jonathan
N1 - Publisher Copyright:
© 2014, Springer-Verlag Berlin Heidelberg.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - Introduction: Infantile hemangiomas are the most common benign tumors in children. However, cranial involvement of such lesions is rare. Current treatment options for hemangiomas in various locations that would be endangering or disfiguring include follow-up, surgical removal, or administration of corticosteroids, interferon-α, thalidomide, vincristine, propranolol, and laser therapy.Methods: We describe an infant who presented with an extensive cranial hemangioma (proven by a biopsy). The child was treated with propranolol.Results: Clinical and radiological follow-up for over a year showed significant reduction in tumor size without adverse clinical symptoms.Conclusion: Propranolol is a valid treatment for large cranial hemangiomas, avoiding the risks involved in surgeries.
AB - Introduction: Infantile hemangiomas are the most common benign tumors in children. However, cranial involvement of such lesions is rare. Current treatment options for hemangiomas in various locations that would be endangering or disfiguring include follow-up, surgical removal, or administration of corticosteroids, interferon-α, thalidomide, vincristine, propranolol, and laser therapy.Methods: We describe an infant who presented with an extensive cranial hemangioma (proven by a biopsy). The child was treated with propranolol.Results: Clinical and radiological follow-up for over a year showed significant reduction in tumor size without adverse clinical symptoms.Conclusion: Propranolol is a valid treatment for large cranial hemangiomas, avoiding the risks involved in surgeries.
KW - Cranial hemangioma
KW - Propranolol
UR - http://www.scopus.com/inward/record.url?scp=84940002204&partnerID=8YFLogxK
U2 - 10.1007/s00381-014-2603-4
DO - 10.1007/s00381-014-2603-4
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C2 - 25472450
AN - SCOPUS:84940002204
SN - 0256-7040
VL - 31
SP - 805
EP - 808
JO - Child's Nervous System
JF - Child's Nervous System
IS - 5
ER -