TY - JOUR
T1 - Giant cobblestone-like papillae during isotretinoin therapy
AU - Rosen, Eli
AU - Raz, Judith
AU - Segev, Fani
PY - 2009/10
Y1 - 2009/10
N2 - Purpose: To report a case of giant cobblestone-like papillae that appeared during oral isotretinoin therapy. Design: Case report. Methods: A 14-year-old boy presented with bilateral eye itching for 1 week. Bilateral upper palpebral conjunctival cobblestone-like papillae, superficial punctate keratitis, and shield ulcer in the left cornea were seen. At the time, he was treated with oral isotretinoin for 6 months. Results: Following cessation of isotretinoin, the ulcer and SPK healed, and the papillae disappeared completely after an 8-week course. Conclusion: Giant cobblestone-like papillae and corneal shield ulcer may be considered as a probable isotretinoin-induced ocular adverse event.
AB - Purpose: To report a case of giant cobblestone-like papillae that appeared during oral isotretinoin therapy. Design: Case report. Methods: A 14-year-old boy presented with bilateral eye itching for 1 week. Bilateral upper palpebral conjunctival cobblestone-like papillae, superficial punctate keratitis, and shield ulcer in the left cornea were seen. At the time, he was treated with oral isotretinoin for 6 months. Results: Following cessation of isotretinoin, the ulcer and SPK healed, and the papillae disappeared completely after an 8-week course. Conclusion: Giant cobblestone-like papillae and corneal shield ulcer may be considered as a probable isotretinoin-induced ocular adverse event.
KW - Acne
KW - Adverse events
KW - Cobblestone-like papillae
KW - Corneal shield ulcer
KW - Isotretinoin
UR - http://www.scopus.com/inward/record.url?scp=70350161628&partnerID=8YFLogxK
U2 - 10.3109/09273940902999364
DO - 10.3109/09273940902999364
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C2 - 19831559
AN - SCOPUS:70350161628
SN - 0927-3948
VL - 17
SP - 312
EP - 313
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 5
ER -