Genomic privacy and limits of individual detection in a pool

Sriram Sankararaman, Guillaume Obozinski, Michael I. Jordan, Eran Halperin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

Recent studies have demonstrated that statistical methods can be used to detect the presence of a single individual within a study group based on summary data reported from genome-wide association studies (GWAS). We present an analytical and empirical study of the statistical power of such methods. We thereby aim to provide quantitative guidelines for researchers wishing to make a limited number of SNPs available publicly without compromising subjects' privacy.

Original languageEnglish
Pages (from-to)965-967
Number of pages3
JournalNature Genetics
Volume41
Issue number9
DOIs
StatePublished - Sep 2009

Funding

FundersFunder number
National Science FoundationIIS-0713254
National Institutes of Health
National Institute of General Medical SciencesR01GM071749
Wellcome Trust076113

    Fingerprint

    Dive into the research topics of 'Genomic privacy and limits of individual detection in a pool'. Together they form a unique fingerprint.

    Cite this