Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis

Keyphrases

• Genetic Basis 100%
• Amyotrophic Lateral Sclerosis 100%
• Genome-wide Identification 100%
• Motor Neuron 40%
• Genome-wide Association Study 40%
• Complex Disease 40%
• KANK1 40%
• Associated Genes 20%
• Heritability 20%
• Functional Genomics 20%
• Fold Increase 20%
• Neurotoxicity 20%
• Machine Learning Approach 20%
• Functional Significance 20%
• Human Neurons 20%
• Gene Discovery 20%
• Induced Pluripotent Stem Cells (iPSCs) 20%
• Heritability Estimates 20%
• Common Variation 20%
• Motor Neuron Disease 20%
• Transcriptomic Profiling 20%
• Brain Tissue 20%
• Patient mutations 20%
• Rare Variation 20%
• TDP-43 Mislocalization 20%
• Epigenetic Profiling 20%
• Transcriptomic Network 20%
• Genetic Convergence 20%
• Rare Variant Analysis 20%
• Axonal Dysfunction 20%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Motor Neuron 100%
• Genome-Wide Association Study 66%
• Candidate Gene 33%
• Functional Genomics 33%
• Epigenetics 33%
• Gene Discovery 33%
• Transcriptomics 33%
• Induced Pluripotent Stem Cell 33%
• Transactive Response Dna Binding Protein-43 33%
• Transcriptome 33%
• Rare Variant 33%