Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder

Shaked Belaish; Ifat Israel-Elgali; Guy Shapira; Israel Krieger; Aviv Segev; Uri Nitzan; Michael Majer; Yuval Bloch; Abraham Weizman; David Gurwitz; Noam Shomron; Libi Hertzberg

doi:10.1038/s41398-021-01529-x

Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder

Shaked Belaish, Ifat Israel-Elgali, Guy Shapira, Israel Krieger, Aviv Segev, Uri Nitzan, Michael Majer, Yuval Bloch, Abraham Weizman, David Gurwitz, Noam Shomron^*, Libi Hertzberg^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Original language	English
Article number	409
Journal	Translational Psychiatry
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41398-021-01529-x
State	Published - Dec 2021

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10.1038/s41398-021-01529-x

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title = "Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder",

author = "Shaked Belaish and Ifat Israel-Elgali and Guy Shapira and Israel Krieger and Aviv Segev and Uri Nitzan and Michael Majer and Yuval Bloch and Abraham Weizman and David Gurwitz and Noam Shomron and Libi Hertzberg",

note = "Funding Information: This work was funded by the Young Investigator Grant from the National Institute of Psychobiology in Israel. The Shomron Laboratory is supported by the Israel Science Foundation (ISF; 1852/16); Israeli Ministry of Defense, Office of Assistant Minister of Defense for Chemical, Biological, Radiological and Nuclear (CBRN) Defense; Foundation Fighting Blindness; The Edmond J. Safra Center for Bioinformatics at Tel Aviv University; The Koret-UC Berkeley-Tel Aviv University Initiative in Computational Biology and Bioinformatics; The QBI/UCSF-Tel Aviv University Joint Initiative in Computational Biology and Drug Discovery. Zimin Institute for Engineering Solutions Advancing Better Lives; Eric and Wendy Schmidt Breakthrough Innovative Research Award; Tel Aviv University Richard Eimert Research Fund on Solid Tumors; Djerassi-Elias Institute of Oncology; Canada-Montreal Friends of Tel Aviv University; Donations from Harold H. Marcus, Amy Friedkin, Natalio Garber, Tal Zohar; Kirschman Dvora Eleonora Fund for Parkinson{\textquoteright}s Disease; Joint funding between Tel Aviv University and Yonsei University; Israeli Ministry of Science and Technology, Israeli–Russia; Aufzien Family Center for the Prevention and Treatment of Parkinson{\textquoteright}s Disease; and a generous donation from the Adelis Foundation; Young Investigator Grant from the National Institute of Psychobiology in Israel. We thank Professor Eytan Domany for his help with the infrastructure that enabled the performance of this project.",

year = "2021",

month = dec,

doi = "10.1038/s41398-021-01529-x",

language = "אנגלית",

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T1 - Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder

AU - Belaish, Shaked

AU - Israel-Elgali, Ifat

AU - Shapira, Guy

AU - Krieger, Israel

AU - Segev, Aviv

AU - Nitzan, Uri

AU - Majer, Michael

AU - Bloch, Yuval

AU - Weizman, Abraham

AU - Gurwitz, David

AU - Shomron, Noam

AU - Hertzberg, Libi

N1 - Funding Information: This work was funded by the Young Investigator Grant from the National Institute of Psychobiology in Israel. The Shomron Laboratory is supported by the Israel Science Foundation (ISF; 1852/16); Israeli Ministry of Defense, Office of Assistant Minister of Defense for Chemical, Biological, Radiological and Nuclear (CBRN) Defense; Foundation Fighting Blindness; The Edmond J. Safra Center for Bioinformatics at Tel Aviv University; The Koret-UC Berkeley-Tel Aviv University Initiative in Computational Biology and Bioinformatics; The QBI/UCSF-Tel Aviv University Joint Initiative in Computational Biology and Drug Discovery. Zimin Institute for Engineering Solutions Advancing Better Lives; Eric and Wendy Schmidt Breakthrough Innovative Research Award; Tel Aviv University Richard Eimert Research Fund on Solid Tumors; Djerassi-Elias Institute of Oncology; Canada-Montreal Friends of Tel Aviv University; Donations from Harold H. Marcus, Amy Friedkin, Natalio Garber, Tal Zohar; Kirschman Dvora Eleonora Fund for Parkinson’s Disease; Joint funding between Tel Aviv University and Yonsei University; Israeli Ministry of Science and Technology, Israeli–Russia; Aufzien Family Center for the Prevention and Treatment of Parkinson’s Disease; and a generous donation from the Adelis Foundation; Young Investigator Grant from the National Institute of Psychobiology in Israel. We thank Professor Eytan Domany for his help with the infrastructure that enabled the performance of this project.

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Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder

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