Genetics of deafness: Recent advances and clinical implications

Abraham Goldfarb, Karen B. Avraham

Research output: Contribution to journalArticlepeer-review


Genetic research into the causes of deafness has advanced considerably in the last years. Progress has been made in both discovering loci and cloning genes associated with syndromic and non-syndromic hearing loss. To date, close to 75 loci have been identified and 29 genes have been cloned for non-syndromic deafness. The proteins these genes encode range from transcription factors to molecular motors to ion channels. We review the recent discoveries and discuss the impact of this research.

Original languageEnglish
Pages (from-to)75-88
Number of pages14
JournalJournal of Basic and Clinical Physiology and Pharmacology
Issue number2
StatePublished - 2002


FundersFunder number
European Economic CommunityQLG2-1999-00988
Israel Ministry of Health
Israel Ministry of Science, Culture & Sport
Israel Science Foundation


    • deafness
    • genes
    • genetic research
    • hearing loss
    • loci


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