@article{4f01c2727d6945e8be3d709dca1c8075,
title = "Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma",
abstract = "We conducted genome-wide association studies of non-Hodgkin lymphoma using Illumina HumanHap550 BeadChips to identify subtype-specific associations in follicular, diffuse large B-cell and chronic lymphocytic leukemia/small lymphocytic lymphomas. We found that rs6457327 on 6p21.33 was associated with susceptibility to follicular lymphoma (FL; N = 189 cases, 592 controls) with validation in another 456 FL cases and 2,785 controls (combined allelic P = 4.7 × 10 -11). The region of strongest association overlapped C6orf15 (STG), located near psoriasis susceptibility region 1 (PSORS1).",
author = "Skibola, {Christine F.} and Bracci, {Paige M.} and Eran Halperin and Lucia Conde and Craig, {David W.} and Luz Agana and Kelly Iyadurai and Nikolaus Becker and Angela Brooks-Wilson and Curry, {John D.} and Spinelli, {John J.} and Holly, {Elizabeth A.} and Jacques Riby and Luoping Zhang and Alexandra Nieters and Smith, {Martyn T.} and Brown, {Kevin M.}",
note = "Funding Information: We thank S. Leach, J. Schuetz and A. MacArthur for assistance. This work was supported by US National Institutes of Health grants CA122663 (C.F.S.), CA104862 (M.T.S.), and CA45614, CA89745 and CA87014 (E.A.H.); the American Cancer Society (IRG-07-06401), the US National Institutes of Health (HL086528) and a charitable donation by Sylvia Chase (K.M.B.); the Stardust Foundation (D.W.C.); the Canadian Cancer Society and National Cancer Institute of Canada, and the Canadian Institutes of Health Research (J.J.S. and A.B.-W.); and the German Jos{\'e} Carreras Leukemia Foundation (DJCLS R04/08 and R07/26f; A.N.).",
year = "2009",
month = aug,
doi = "10.1038/ng.419",
language = "אנגלית",
volume = "41",
pages = "873--875",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Research",
number = "8",
}
