Genetic factors in neuromuscular pain

Dan Buskila, Lily Neumann, Joseph Press

Research output: Contribution to journalReview articlepeer-review

Abstract

Recent evidence suggests that fibromyalgia, a chronic widespread pain condition and related syndromes (chronic fatigue syndrome, irritable bowel syndrome, etc.) may share heritable pathophysiologic features. We review the recent literature on genetic and familial factors found to participate in the pathogenesis of these syndromes, specifically fibromyalgia, including evidence suggesting that serotonin- and dopamine-related genes may play a role in the pathogenesis of these illnesses. The importance of environmental factors triggering these conditions in predisposed individuals is also discussed.

Original languageEnglish
Pages (from-to)281-284
Number of pages4
JournalCNS Spectrums
Volume10
Issue number4
DOIs
StatePublished - Apr 2005
Externally publishedYes

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