Generalized lymphadenitis following B.C.G. vaccination in an immunocompetent 12-year-old boy

Z. Katzir*, E. Okon, A. Ludmirski, Y. Sherman, H. Haas

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


An immunocompetent, healthy 12-year-old boy was presented with generalized large lymphadenopathy in the left side of the body, 1 month after a BCG vaccination with a regular dose. A Mantoux test before vaccination was negative. Histological and bacteriological findings from the largest lymph node biopsy revealed BCG'itis. The patient recovered sponaneously after 7 months. He was confirmed as being immunocompetent by normal serum immunoglobulin levels, normal B and T cell function tests, and a conversion of Mantoux test. BCG infections including lymphadenitis are rare and have been described hitherto mainly in infants, in immune deficient patients, or related to overdose. Such a complication must be taken into consideration when dealing with lymphadenopathy in healthy school-age children, who now undergo BCG vaccinations in many countries.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalEuropean Journal of Pediatrics
Issue number3
StatePublished - Jan 1984
Externally publishedYes


  • BCG-Adverse reactions
  • Lymphadenitis


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