Gastrointestinal events related to the use of non-steroidal anti-inflammatory drugs: Some clinical and economic aspects

R. Eliakim, D. Rachmilewitz

Research output: Contribution to journalShort surveypeer-review

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most widely prescribed drugs for arthritic and musculoskelatal disorders in the US. Moreover, aspirin is effective in the prevention of myocardial infarction, graft occlusion and strike, and in the treatment of acute myocardial infarction, unstable angina pectoris and transient ischemic attacks. However, while NSAIDs are economically attractive, gastrointestinal (GI) side-effects from these drugs are common. The overall odds ratio of the risk for adverse GI events related to NSAIDs use at 2.74.

Original languageEnglish
Pages (from-to)696-699
Number of pages4
JournalIsrael Journal of Medical Sciences
Volume33
Issue number10
StatePublished - Oct 1997
Externally publishedYes

Keywords

  • Bleeding
  • Duodenal ulcer
  • Gastric ulcer
  • NSAIDs
  • Perforation

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