Ganciclovir treatment in Ménétrier's disease

A 2-y-old girl with severe edema, oliguria and hypoalbuminemia caused by protein-losing gastritis was diagnosed with cytomegalovirus-associated Ménétrier's disease. After almost two weeks, during which the patient required repeated albumin transfusions, she was treated with intravenous ganciclovir. Within five days her condition had improved, and no additional albumin replacement was needed. Complete recovery was observed after several weeks. Conclusion: In patients with severe Ménétrier's disease, a course of ganciclovir treatment may be of benefit and should be considered.