Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells

Keyphrases

• Molecular Switches 100%
• K-ras 100%
• N-Ras 100%
• Galectin-3 (Gal-3) 100%
• Human Breast Carcinoma Cells 100%
• Extracellular Signal-regulated Kinase 16%
• Ras Activation 16%
• BT549 16%
• Cancer Progression 8%
• Overexpression 8%
• Functional Role 8%
• Binding Partners 8%
• Ras Isoforms 8%
• Farnesylthiosalicylic Acid 8%
• Anti-apoptotic 8%
• Growth Function 8%
• Mutant Protein 8%
• Specific Inhibitor 8%
• RAS Pathway 8%
• Anchorage-independent Growth 8%
• Oncogenic Kras 8%
• Molecular Function 8%
• Selective Binding 8%
• Human Breast Cancer Cells 8%
• UO126 8%
• Oncogenic Function 8%
• Mitogen-activated Protein 8%
• Apoptotic Resistance 8%
• Isoform Switching 8%
• Carbohydrate-binding Protein 8%

Biochemistry, Genetics and Molecular Biology

• Galectin-3 100%
• Wild Type 33%
• Guanosine Triphosphate 25%
• Extracellular Signal-Regulated Kinases 16%
• Signal Transduction 8%
• Cancer Cell 8%
• Binding Protein 8%
• Isoform 8%
• Kinase 8%
• Phosphotransferase 8%
• Mutant Protein 8%
• Anchorage Independent Growth 8%