TY - JOUR
T1 - Ga-67 SPECT before and after treatment of lymphoma
AU - Front, Dov
AU - Israel, Ora
AU - Epelbaum, Ron
AU - Haim, Simona Ben
AU - Sapir, Einat Even
AU - Jerushalmi, Jacqueline
AU - Kolodny, Gerald M.
AU - Robinson, Eliezer
PY - 1990/5
Y1 - 1990/5
N2 - The results of planar and single photon emission computed tomography (SPECT) gallium-67 scintigraphy performed before and after treatment were compared in 77 patients with lymphoma at 240 sites. Before treatment, the sensitivity of planar scintigraphy was 78% and the specificity was 97%; after treatment, 84% and 96%, respectively. Before treatment, SPECT had a sensitivity of 85% and a specificity of 98%; after treatment, 92% and 99%, respectively. In addition, SPECT allowed better anatomical localization and showed the entire extent of lesions at 36 sites. SPECT was of special value after treatment in excluding disease at 16 sites with residual masses seen at computed tomography (CT). Long-term follow-up in these patients showed that their condition was in complete remission and that the CT appearance of a residual mass does not always mean residual cancer. Thus, Ga-67 SPECT is a suitable imaging technique for monitoring the response of lymphoma to treatment.
AB - The results of planar and single photon emission computed tomography (SPECT) gallium-67 scintigraphy performed before and after treatment were compared in 77 patients with lymphoma at 240 sites. Before treatment, the sensitivity of planar scintigraphy was 78% and the specificity was 97%; after treatment, 84% and 96%, respectively. Before treatment, SPECT had a sensitivity of 85% and a specificity of 98%; after treatment, 92% and 99%, respectively. In addition, SPECT allowed better anatomical localization and showed the entire extent of lesions at 36 sites. SPECT was of special value after treatment in excluding disease at 16 sites with residual masses seen at computed tomography (CT). Long-term follow-up in these patients showed that their condition was in complete remission and that the CT appearance of a residual mass does not always mean residual cancer. Thus, Ga-67 SPECT is a suitable imaging technique for monitoring the response of lymphoma to treatment.
KW - Emission CT
KW - Gallium, radioactive
KW - Hodgkin disease
KW - Lymphoma, CT
KW - Lymphoma, radionuclide studies
UR - http://www.scopus.com/inward/record.url?scp=0025208378&partnerID=8YFLogxK
U2 - 10.1148/radiology.175.2.2183289
DO - 10.1148/radiology.175.2.2183289
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C2 - 2183289
AN - SCOPUS:0025208378
SN - 0033-8419
VL - 175
SP - 515
EP - 519
JO - Radiology
JF - Radiology
IS - 2
ER -
