TY - JOUR
T1 - Functional Carbon Quantum Dots for Ocular Imaging and Therapeutic Applications
AU - Kumar, Vijay Bhooshan
AU - Sher, Ifat
AU - Rencus-Lazar, Sigal
AU - Rotenstreich, Ygal
AU - Gazit, Ehud
N1 - Publisher Copyright:
© 2022 The Authors. Small published by Wiley-VCH GmbH.
PY - 2023/2/15
Y1 - 2023/2/15
N2 - Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have received considerable attention due to their excellent fluorescent properties, extremely small size, ability to penetrate cells and tissues, ease of synthesis, surface modification, low cytotoxicity, and superior water dispersion. In light of these properties, CDs are extensively investigated as candidates for bioimaging probes, efficient drug carriers, and disease diagnostics. Functionalized CDs represent a promising therapeutic candidate for ocular diseases. Here, this work reviews the potential use of functionalized CDs in the diagnosis and treatment of eye-related diseases, including the treatment of macular and anterior segment diseases, as well as targeting Aβ amyloids in the retina.
AB - Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have received considerable attention due to their excellent fluorescent properties, extremely small size, ability to penetrate cells and tissues, ease of synthesis, surface modification, low cytotoxicity, and superior water dispersion. In light of these properties, CDs are extensively investigated as candidates for bioimaging probes, efficient drug carriers, and disease diagnostics. Functionalized CDs represent a promising therapeutic candidate for ocular diseases. Here, this work reviews the potential use of functionalized CDs in the diagnosis and treatment of eye-related diseases, including the treatment of macular and anterior segment diseases, as well as targeting Aβ amyloids in the retina.
KW - age-related macular degeneration
KW - carbon quantum dots
KW - ocular imaging
KW - ophthalmic diseases
UR - http://www.scopus.com/inward/record.url?scp=85143525259&partnerID=8YFLogxK
U2 - 10.1002/smll.202205754
DO - 10.1002/smll.202205754
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C2 - 36461689
AN - SCOPUS:85143525259
SN - 1613-6810
VL - 19
JO - Small
JF - Small
IS - 7
M1 - 2205754
ER -