Functional Carbon Quantum Dots for Ocular Imaging and Therapeutic Applications

Vijay Bhooshan Kumar, Ifat Sher, Sigal Rencus-Lazar, Ygal Rotenstreich, Ehud Gazit*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have received considerable attention due to their excellent fluorescent properties, extremely small size, ability to penetrate cells and tissues, ease of synthesis, surface modification, low cytotoxicity, and superior water dispersion. In light of these properties, CDs are extensively investigated as candidates for bioimaging probes, efficient drug carriers, and disease diagnostics. Functionalized CDs represent a promising therapeutic candidate for ocular diseases. Here, this work reviews the potential use of functionalized CDs in the diagnosis and treatment of eye-related diseases, including the treatment of macular and anterior segment diseases, as well as targeting Aβ amyloids in the retina.

Original languageEnglish
Article number2205754
JournalSmall
Volume19
Issue number7
DOIs
StatePublished - 15 Feb 2023

Keywords

  • age-related macular degeneration
  • carbon quantum dots
  • ocular imaging
  • ophthalmic diseases

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