Abstract
Polymorphism of the FTO gene encoding an N6-methyladenosine (m6A) RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood. A new study published in Cell Research reports novel functions implicating FTO in the regulation of mRNA alternative splicing in the control of adipogenesis.
Original language | English |
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Pages (from-to) | 3-4 |
Number of pages | 2 |
Journal | Cell Research |
Volume | 25 |
Issue number | 1 |
DOIs |
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State | Published - 5 Jan 2015 |