From pharmacogenetics to personalized medicine: A vital need for educating health professionals and the community

Felix W. Frueh*, David Gurwitz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

110 Scopus citations

Abstract

The field of pharmacogenetics will soon celebrate its 50th anniversary. Although science has delivered an impressive amount of information in these 50 years, pharmacogenetics has suffered from lack of integration into clinical practice. There are several reasons for this, including the unmet need for education at medical schools and the lack of awareness about the impact of genetic medicine on healthcare in the community. Recently, the FDA announced that it considers pharmacogenomics one of three major opportunities on the critical path to new medical products. This notion by the FDA is filling the regulatory void that existed between drug developers and drug users. However, in order to bring pharmacogenetic testing to the prescription pad successfully, healthcare professionals and policy makers, as well as patients, need to have the necessary background knowledge for making educated treatment decisions. To effectively move pharmacogenetics into everyday medicine, it is therefore imperative for scientists and teachers in the field to take on the challenge of disseminating pharmacogenetic insights to a broader audience. 2004

Original languageEnglish
Pages (from-to)571-579
Number of pages9
JournalPharmacogenomics
Volume5
Issue number5
DOIs
StatePublished - Jul 2004

Keywords

  • Adverse drug reactions
  • Bioethics
  • CYP450 enzymes
  • FDA guidelines
  • Medical education
  • Personalized medicine
  • Pharmacodynamics
  • Pharmacogenetics
  • Pharmacogenomics
  • Pharmacokinetics
  • Population studies

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