From carboxylic acids to the trifluoromethyl group using BrF3

Or Cohen, Eyal Mishani, Shlomo Rozen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Organic trifluoromethyl derivatives were made from aromatic and aliphatic carboxylic acids by transforming them first into the corresponding dithioesters followed by reaction with bromine trifluoride under mild conditions (0 °C, 2 min).

Original languageEnglish
Pages (from-to)3579-3582
Number of pages4
JournalTetrahedron
Volume66
Issue number20
DOIs
StatePublished - 15 May 2010

Funding

FundersFunder number
USA-Israel Binational Science Foundation
United States-Israel Binational Science Foundation

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