Frameless stereotactic procedures in pediatric patients: Safety and diagnostic efficacy

Mary G. Parreño, Xiao Bo, Okezie O. Kanu, Shlomi Constantini, Andrew A. Kanner

Research output: Contribution to journalArticlepeer-review


Purpose: The aim of our retrospective study was to evaluate the feasibility, safety, and diagnostic yield of a frameless method for stereotactic neurosurgical procedures in pediatric patients. Methods: Twenty-two frameless stereotactic neurosurgical procedures (18 biopsies, 4 catheter placements), using a modified frameless stereotactic navigational system, were performed in 21 pediatric patients in our institution from 2004 to 2009. All procedures were performed by the senior authors (AAK, SC). Results: We completed 18 biopsy procedures in 18 patients, yielding usable diagnostic specimens in 100% of the procedures. Of this biopsy group, two patients experienced an asymptomatic hemorrhage per CT, and one patient experienced a transient hemiparesis, recovering to baseline within 1 week after surgery. Four catheter placement procedures were completed in three patients, including one patient who had to have the procedure repeated. We had no peri-operative mortality or technical difficulties related to the catheter placements. Conclusions: Frameless stereotactic neurosurgical procedures in the pediatric population are feasible and can be completed safely for histological tumor diagnosis as well as for accurate placement of intracranial catheters. This method has low rates of morbidity comparable to frame-based procedures, with the advantage of greater operative convenience.

Original languageEnglish
Pages (from-to)2137-2140
Number of pages4
JournalChild's Nervous System
Issue number12
StatePublished - Dec 2011


  • Brain biopsy
  • Brain tumor
  • Catheter placement
  • Frameless
  • Pediatric
  • Stereotactic


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