Formation of histiocytes by the omentum in vitro

M. Aronson*, A. Shahar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


1. 1. When omental fragments of the rabbit, the guinea-pig or the mouse were cultivated in vitro, large numbers of histiocytes and of fibroblasts migrated from the expiants. Upon serial transfer, throughout several weeks, new generations of both types of cells were obtained. 2. 2. The results of autoradiographic studies indicated that both the histiocytes and the fibroblasts were generated in vitro. 3. 3. An attempt was made to ascertain whether both eell types came from a common stem-cell or from two distinct lines. The results were compatible with the theory that histiocytes and fibroblasts come from one precursor cell. 4. 4. The significance of the results is discussed in relation to the source of cells in inflammation.

Original languageEnglish
Pages (from-to)133-143
Number of pages11
JournalExperimental Cell Research
Issue number1
StatePublished - Apr 1965
Externally publishedYes


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