TY - JOUR
T1 - Formation and characterization of stable human serum albumin-tris-malonic acid [C60]fullerene complex
AU - Belgorodsky, Bogdan
AU - Fadeev, Ludmila
AU - Ittah, Varda
AU - Benyamini, Hadar
AU - Zelner, Stanislav
AU - Huppert, Dan
AU - Kotlyar, Alexander B.
AU - Gozin, Michael
PY - 2005
Y1 - 2005
N2 - The preparation and characterization of the stable human serum albumin (HSA)-C3 isomer of tris-malonic acid [C60]fullerene complex is reported. Other than the anti-fullerene antibody, a stable protein-fullerene complex with a native protein has never been observed. This study may provide valuable answers to the growing concern regarding the effects of carbonaceous nanomaterials on human health on one hand and, on the other, may lead to the development of novel antioxidant therapeutic agents, radiopharmaceuticals, and components for bioelectronic devices.
AB - The preparation and characterization of the stable human serum albumin (HSA)-C3 isomer of tris-malonic acid [C60]fullerene complex is reported. Other than the anti-fullerene antibody, a stable protein-fullerene complex with a native protein has never been observed. This study may provide valuable answers to the growing concern regarding the effects of carbonaceous nanomaterials on human health on one hand and, on the other, may lead to the development of novel antioxidant therapeutic agents, radiopharmaceuticals, and components for bioelectronic devices.
UR - http://www.scopus.com/inward/record.url?scp=25444434635&partnerID=8YFLogxK
U2 - 10.1021/bc050103c
DO - 10.1021/bc050103c
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AN - SCOPUS:25444434635
SN - 1043-1802
VL - 16
SP - 1058
EP - 1062
JO - Bioconjugate Chemistry
JF - Bioconjugate Chemistry
IS - 5
ER -
