For Debate: Growth Hormone Treatment of Infants Born Small for Gestational Age should be Started at or before the First Year of Age

Zvi Laron, Tamar Laron-Kenet, Gil Klinger

Research output: Contribution to journalArticlepeer-review

Abstract

Children born small for gestational age without early catch-up of somatic growth and head circumference subsequently remain short and suffer from various degrees of neurocognitive and psychological impairment. Based upon the role of growth hormone (GH) and insulin-like growth factor-I on early brain growth and maturation, we propose that GH treatment of these infants be instituted prior to their 2nd birthday.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalPediatric Endocrinology Reviews
Volume14
Issue number2
DOIs
StatePublished - 1 Dec 2016

Keywords

  • Cognitive deficit
  • GH treatment
  • Learning difficulties
  • Neuro-Motor retardation
  • Short stature
  • Small for Gestational Age (SGA)

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