Follicular lymphoma with extensive gastrointestinal tract involvement: Follow-up by capsule endoscopy

Boris Sapoznikov, Sarah Morgenstern, Pia Raanani, Adina Aviram, Esther Rabizadeh, Miron Prokocimer, Yaron Niv

Research output: Contribution to journalArticlepeer-review

Abstract

Follicular lymphoma with gastrointestinal tract involvement is rare. We describe the case of a young woman with follicular lymphoma with multiple nodular lesions involving segments of the proximal jejunum and terminal ileum. The presenting symptom was chronic diarrhea. The diagnosis was made by endoscopy with histologic examination of the mucosal lesions of the proximal and distal small intestine, immunohistochemical staining, and molecular analysis. The initial spread and pattern of the small bowel involvement, as well as treatment response, were evaluated by videocapsule endoscopy. The application of molecular analysis along with immunophenotypic evaluation has made it possible to precisely diagnose follicular lymphoma. In the present case, the use of capsule endoscopy improved the evaluation of the extent of small bowel involvement prior to and following treatment.

Original languageEnglish
Pages (from-to)1031-1035
Number of pages5
JournalDigestive Diseases and Sciences
Volume52
Issue number4
DOIs
StatePublished - Apr 2007

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