Folding of two large nucleotide chains

Ruth Nussinov*, George Pieczenik

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We have already described the FOLD-A code designed for folding mRNA's and single stranded DNA molecules (Nussinov & Pieczenik, 1984). In this paper we describe its application to two long polynucleotide chains: the A protein gene of the MS2 RNA and the whole genome of the φX 174 phage. The folded form of the single stranded DNA of the φX 174 is a six armed star with the origin of replication in its center.

Original languageEnglish
Pages (from-to)261-273
Number of pages13
JournalJournal of Theoretical Biology
Issue number3
StatePublished - 7 Feb 1984
Externally publishedYes


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