TY - JOUR
T1 - Folding of two large nucleotide chains
AU - Nussinov, Ruth
AU - Pieczenik, George
N1 - Funding Information:
To Dr Barbara Brodsky of the Rutgers’ Medical School, we express our thanks for her continuing interest and encouragement during the course of our work. We would also like to thank C.C.I.S., Hill Center at Rutgers’ University for computer facilities. This work was supported in part by grant NIH-GM.
PY - 1984/2/7
Y1 - 1984/2/7
N2 - We have already described the FOLD-A code designed for folding mRNA's and single stranded DNA molecules (Nussinov & Pieczenik, 1984). In this paper we describe its application to two long polynucleotide chains: the A protein gene of the MS2 RNA and the whole genome of the φX 174 phage. The folded form of the single stranded DNA of the φX 174 is a six armed star with the origin of replication in its center.
AB - We have already described the FOLD-A code designed for folding mRNA's and single stranded DNA molecules (Nussinov & Pieczenik, 1984). In this paper we describe its application to two long polynucleotide chains: the A protein gene of the MS2 RNA and the whole genome of the φX 174 phage. The folded form of the single stranded DNA of the φX 174 is a six armed star with the origin of replication in its center.
UR - http://www.scopus.com/inward/record.url?scp=0021756725&partnerID=8YFLogxK
U2 - 10.1016/0022-5193(84)90030-4
DO - 10.1016/0022-5193(84)90030-4
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AN - SCOPUS:0021756725
SN - 0022-5193
VL - 106
SP - 261
EP - 273
JO - Journal of Theoretical Biology
JF - Journal of Theoretical Biology
IS - 3
ER -