TY - JOUR
T1 - Fmoc-diphenylalanine gelating nanoarchitectonics
T2 - A simplistic peptide self-assembly to meet complex applications
AU - Wang, Yunxiao
AU - Geng, Qiang
AU - Zhang, Yan
AU - Adler-Abramovich, Lihi
AU - Fan, Xinyuan
AU - Mei, Deqing
AU - Gazit, Ehud
AU - Tao, Kai
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2023/4/15
Y1 - 2023/4/15
N2 - 9-fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF), has been has been extensively explored due to its ultrafast self-assembly kinetics, inherent biocompatibility, tunable physicochemical properties, and especially, the capability of forming self-sustained gels under physiological conditions. Consequently, various methodologies to develop Fmoc-FF gels and their corresponding applications in biomedical and industrial fields have been extensively studied. Herein, we systemically summarize the mechanisms underlying Fmoc-FF self-assembly, discuss the preparation methodologies of Fmoc-FF hydrogels, and then deliberate the properties as well as the diverse applications of Fmoc-FF self-assemblies. Finally, the contemporary shortcomings which limit the development of Fmoc-FF self-assembly are raised and the alternative solutions are proposed, along with future research perspectives.
AB - 9-fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF), has been has been extensively explored due to its ultrafast self-assembly kinetics, inherent biocompatibility, tunable physicochemical properties, and especially, the capability of forming self-sustained gels under physiological conditions. Consequently, various methodologies to develop Fmoc-FF gels and their corresponding applications in biomedical and industrial fields have been extensively studied. Herein, we systemically summarize the mechanisms underlying Fmoc-FF self-assembly, discuss the preparation methodologies of Fmoc-FF hydrogels, and then deliberate the properties as well as the diverse applications of Fmoc-FF self-assemblies. Finally, the contemporary shortcomings which limit the development of Fmoc-FF self-assembly are raised and the alternative solutions are proposed, along with future research perspectives.
UR - http://www.scopus.com/inward/record.url?scp=85145976408&partnerID=8YFLogxK
U2 - 10.1016/j.jcis.2022.12.166
DO - 10.1016/j.jcis.2022.12.166
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 36623365
AN - SCOPUS:85145976408
SN - 0021-9797
VL - 636
SP - 113
EP - 133
JO - Journal of Colloid and Interface Science
JF - Journal of Colloid and Interface Science
ER -
