TY - JOUR
T1 - Fluorine-18 Fluorodeoxyglucose PET/CT Patterns of Extranodal Involvement in Patients with Non-Hodgkin Lymphoma and Hodgkin's Disease
AU - Even-Sapir, Einat
AU - Lievshitz, Genady
AU - Perry, Chava
AU - Herishanu, Yair
AU - Lerman, Hedva
AU - Metser, Ur
PY - 2006/7
Y1 - 2006/7
N2 - Lymphoma may originate in extranodal sites. ENL may also be secondary to and accompany nodal disease. ENL is probably more common than previously thought, with an incidence of approximately 25% in the overall population of patients with lymphoma, which may be even higher in some specific subtypes, such as MALT. 18F-FDG imaging has an essential role in the staging of lymphoma, in monitoring the response to therapy, and in detection of recurrence. The introduction of 18F-FDG PET/CT hybrid imaging allows for accurate localization of disease and may be specifically beneficial for the detection of unexpected extranodal sites of disease or exclusion of disease in the presence of nonspecific extranodal CT findings. Accurate staging and localization often dictate the appropriate treatment strategy in patients with lymphoma. Therefore, at any stage in the course of the disease, the potential presence of extranodal disease should be considered when interpreting 18F-FDG PET/CT studies in patients with NHL and HD.
AB - Lymphoma may originate in extranodal sites. ENL may also be secondary to and accompany nodal disease. ENL is probably more common than previously thought, with an incidence of approximately 25% in the overall population of patients with lymphoma, which may be even higher in some specific subtypes, such as MALT. 18F-FDG imaging has an essential role in the staging of lymphoma, in monitoring the response to therapy, and in detection of recurrence. The introduction of 18F-FDG PET/CT hybrid imaging allows for accurate localization of disease and may be specifically beneficial for the detection of unexpected extranodal sites of disease or exclusion of disease in the presence of nonspecific extranodal CT findings. Accurate staging and localization often dictate the appropriate treatment strategy in patients with lymphoma. Therefore, at any stage in the course of the disease, the potential presence of extranodal disease should be considered when interpreting 18F-FDG PET/CT studies in patients with NHL and HD.
UR - http://www.scopus.com/inward/record.url?scp=33845226659&partnerID=8YFLogxK
U2 - 10.1016/j.cpet.2006.04.007
DO - 10.1016/j.cpet.2006.04.007
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AN - SCOPUS:33845226659
SN - 1556-8598
VL - 1
SP - 251
EP - 263
JO - PET Clinics
JF - PET Clinics
IS - 3
ER -
