Fluorination of α,β-unsaturated carbonyl compounds using elemental fluorine

Inna Vints, Shlomo Rozen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Elemental fluorine was successfully added across the double bond of various α,β-unsaturated carbonyl compounds. A necessary ingredient is a presence of alcohol in the solvent mixture. Unlike all other halogen's addition to olefins, fluorine adds itself in a syn mode specificity. The vic difluoro products were easily dehydrofluorinated to form the corresponding α-fluoro carbonyl derivatives.

Original languageEnglish
Pages (from-to)632-636
Number of pages5
JournalTetrahedron
Volume72
Issue number5
DOIs
StatePublished - 4 Feb 2016

Funding

FundersFunder number
Israel Science Foundation

    Keywords

    • Dehydrofluorination
    • Elemental fluorine
    • Enones fluorination
    • Fluoro enones
    • syn Addition

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